CRPS Type I
Complex regional pain syndrome can cause disproportionate regional pain, sensitivity, color or temperature change, swelling, and movement limitation without a confirmed major nerve injury.
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Dorsal root ganglion stimulation is an implantable neuromodulation treatment for carefully selected adults with chronic, focal neuropathic pain. The FDA-approved system targets moderate to severe chronic intractable pain of the lower limbs associated with complex regional pain syndrome types I or II.
The dorsal root ganglion is a cluster of sensory nerve-cell bodies near each spinal nerve root. Stimulation at a specific level can focus therapy on a painful region such as the foot, ankle, knee, groin, or another lower-limb distribution.
A temporary trial allows the patient and clinician to measure benefit before considering a permanent implant. The goal is better function and quality of life, not a guarantee of complete pain elimination.
Dorsal root ganglion stimulation uses implanted leads near selected DRGs to modify focal neuropathic pain signals, with a required trial phase before long-term implantation.

DRG stimulation delivers mild electrical pulses near the sensory gateway that carries information from a defined body region into the spinal cord.
Traditional spinal cord stimulation often covers broader areas. DRG therapy is designed for more focused targeting and may be less affected by body position, although device response varies by patient and programming.
The system includes one or more leads, an implanted pulse generator, and an external controller or programmer. Programming is individualized and may be adjusted over time.
Candidacy is specific and includes diagnosis, prior treatment, psychological and functional evaluation, device safety, and trial response.
Complex regional pain syndrome can cause disproportionate regional pain, sensitivity, color or temperature change, swelling, and movement limitation without a confirmed major nerve injury.
Similar regional symptoms may follow a known nerve injury. DRG stimulation is FDA approved for selected chronic intractable lower-limb CRPS I or II pain.
A clearly localized distribution and prior treatment failure may prompt specialist evaluation within device labeling and current evidence.
Permanent implantation is considered only after meaningful trial benefit and the patient demonstrates understanding of device care, follow-up, and realistic goals.
Neuropathic pain can be severe even when tissue healing appears complete. A full evaluation is needed to confirm the diagnosis and rule out an urgent cause.
The evaluation confirms the neuropathic diagnosis, identifies the target distribution, and determines whether an implantable therapy is safe and practical.
The clinician maps symptoms, sensory change, autonomic findings, prior nerve injury, surgery, and whether the pattern fits CRPS or another focal neuropathic condition.
Medication, rehabilitation, blocks, psychological care, and other procedures are reviewed alongside walking, sleep, work, and daily goals.
Imaging and testing assess spinal anatomy, infection and bleeding risk, and other conditions that could explain symptoms or affect implantation.
Evaluation addresses coping, expectations, cognition, substance-use risk, support, and the ability to manage charging or controller tasks when applicable.
A trial comes first. It provides direct information about target coverage, comfort, function, and whether long-term implantation is reasonable.
Pain distribution, medication use, walking, sleep, and specific functional goals are documented before stimulation begins.
Under fluoroscopy, leads are advanced into the epidural space and positioned near selected dorsal root ganglia.
The leads connect to an external generator. Programming is adjusted while the patient tests normal, safe daily activities and records response.
The team evaluates pain change, function, medication, sleep, stimulation comfort, and practical device experience—not pain percentage alone.
If the trial is successful, permanent leads and an internal pulse generator are implanted, followed by wound care, restrictions, and programming.

Early movement restrictions protect lead position and incisions. Ongoing programming and self-management are part of long-term care.
Follow restrictions for bending, twisting, lifting, reaching, bathing, driving, and exercise while tissues anchor around the leads.
Several sessions may be needed to refine coverage and comfort. Contact the team if stimulation becomes unpleasant or benefit changes.
A gradual movement and desensitization plan can help translate symptom improvement into walking, strength, confidence, and daily function.
Carry device information and follow current manufacturer instructions for MRI, surgery, security systems, driving, charging, and other equipment.
DRG stimulation may provide focused, adjustable therapy for a difficult pain condition, but trial success cannot guarantee the long-term result.
Risks include bleeding, infection, dural puncture, nerve injury, lead movement or breakage, pain at the implant, hardware malfunction, uncomfortable stimulation, and loss of benefit.
Call 911 for severe weakness, breathing difficulty, loss of consciousness, or another life-threatening emergency.
Neuromodulation is most useful when it supports a broader plan for movement, desensitization, coping, sleep, and meaningful activity.
Graded movement, gait training, desensitization, mirror-based strategies, and functional restoration may help prevent long-term disuse.
Nerve-pain medication and other agents may be adjusted gradually according to response and side effects.
Pain-focused psychological care can improve coping, pacing, sleep, and confidence without suggesting that pain is imagined.
Programming, battery management, activity planning, and periodic review help maintain safe, useful treatment over time.
California Pain Consultants can evaluate chronic focal neuropathic pain, review prior treatment, and explain the dorsal root ganglion stimulation trial, implant, alternatives, and realistic goals.
Book an appointmentMedical references: FDA: Axium DRG neurostimulator approval · FDA: DRG stimulator product classification.
Related California Pain resources: Complex regional pain syndrome · Neuropathy · Phantom limb pain.
This article is for general education and does not replace an individualized medical evaluation. Recommendations depend on the diagnosis, health history, current medications, imaging, examination, and personal goals.
Find clear, medically responsible answers about Dorsal Root Ganglion Stimulation, who may be a candidate, what to expect, and when to contact your healthcare team.
Dorsal root ganglion stimulation is a type of neuromodulation that delivers mild electrical pulses to a small cluster of sensory nerve cells near the spine. By targeting the DRG associated with a painful region, it can offer focused coverage for certain localized neuropathic pain patterns.
It may be considered for selected chronic neuropathic pain conditions, including complex regional pain syndrome or causalgia affecting a lower limb. Other focal nerve-pain patterns may be considered depending on the diagnosis, device indication, and specialist assessment.
Potential candidates generally have persistent, function-limiting neuropathic pain despite appropriate conservative and interventional care. Evaluation includes diagnosis, imaging when needed, medication and psychological review, infection risk, expectations, and ability to participate in a temporary trial and ongoing device care.
Before a trial, follow instructions about blood thinners, fasting, infection prevention, and transportation. Discuss work duties, activity limits, current implanted devices, and MRI needs so the team can plan safely.
Temporary leads are positioned near selected dorsal root ganglia under imaging guidance and connected to an external controller for a trial. If the trial meets agreed-upon functional and pain goals, a pulse generator may later be implanted under the skin.
Incision soreness and temporary bending, lifting, and twisting restrictions are expected after lead placement or implantation. Follow-up programming is important to optimize coverage while the leads heal in place.
A trial is used to judge benefit over several days before committing to a permanent system. Long-term response varies, and programming adjustments, charging or controller routines, and periodic device checks may be needed.
Possible risks include bleeding, infection, lead movement or breakage, uncomfortable stimulation, nerve injury, headache from spinal-fluid leak, device malfunction, or loss of benefit. Revision or removal can sometimes be necessary.
DRG stimulation is intended to support function and quality of life, not cure the underlying condition. It is commonly combined with rehabilitation, medication review, sleep and behavioral support, and treatment of any ongoing medical contributors.
Call the implanting team for fever, drainage, increasing redness, severe new pain, a sudden change in stimulation, or loss of device function. Seek emergency care for progressive weakness, new bowel or bladder problems, saddle numbness, chest pain, or trouble breathing.
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